Buffalo's Week 5 inactive list reshapes the depth chart. Dorian Williams and Dorian Strong sit out, Elijah Moore and Jordan Hancock join the bench, and Ed Oliver and TJ Sanders are sidelined on the defensive line, tangling Buffalo's fantasy floor at multiple spots. New England counters with Chaisson, Gregory, Wallace, Chism, and DeVito out, narrowing contingency plans and elevating backup options.

Patriots-Bills Week 5 inactives reshape fantasy expectations. Carlton Davis and Milton Williams are active, anchoring New England’s secondary and interior line as Jahlani Tavai returns. K'Lavon Chaisson is out, likely boosting Keion White’s rush opportunities against Josh Allen. Efton Chism III remains inactive, stalling rookie WR upside.

Bills list Elijah Moore, Ed Oliver, Dorian Williams, Jordan Hancock, Brandon Codrington, Chase Lundt, and T. J. Sanders as inactive, signaling clearer target trees and fewer interior disruptors for Buffalo. Snap and scheme shifts could tilt value on both sides, especially for edge rushers and defensive units in DFS.

New England patched the roster ahead of the Bills game: K'Lavon Chaisson is out, Jahlani Tavai is back from IR, and Milton Williams travels with the team though limited by an ankle issue. Chaisson’s absence flags Keion White for more edge reps, potentially setting up a breakout against Josh Allen. Williams’ status adds a potential interior disruptor if he can go, while Tavai’s return stabilizes New England’s linebacker group in a must-win matchup.

New England Patriots Week 5 injury report ahead of the primetime clash with Buffalo shows key questions on the edge and in the secondary. K'Lavon Chaisson knee and Jaylinn Hawkins hamstring leave both outside linebackers and safeties in flux, while Jahlani Tavai returns as a limited participant after IR. Several Patriots linemen and linebackers logged limited work, and Will Campbell came back to full participation after a shoulder issue. Bills' side lists multiple non-participants or limited players as well, setting up a high-stakes fantasy showcase.

Buffalo’s Dorian Williams knee kept him out, Matt Milano (pectoral) and Ed Oliver (ankle) were limited, Spencer Brown (calf) and Jackson Hawes (ankle) followed with limited practice. No Bills players were listed as fully participating. The Week 5 picture hinges on edge depth, LB rotation, and the health of interior lines, with fantasy managers eyeing snap shares and potential upside if injuries linger.

Harold Landry III’s Week 1 surge for New England is a fantasy spark. Five tackles and 2.5 sacks anchored NE’s edge rush, with Landry leading the league in sacks through the season’s opening stretch. He joined the Patriots this winter after a Tennessee run, was voted a defensive captain, and immediately energized a front that paired him with K'Lavon Chaisson and Milton Williams for first-half pressure, giving NE a 10-7 edge before Las Vegas answered. The challenge now is sustaining that pace into the second half and beyond, turning individual success into team consistency.

Landry’s BC pedigree and Vrabel-era history add intrigue to NE’s design. If the pass rush can translate early energy into four quarters, fantasy managers should monitor each edge rotation and game script for sack upside. The defense flashed dominant moments; the real test will be eliminating lapses and maintaining the rhythm as Weeks 2 and 3 approach.