New England travels south off a primetime upset of Buffalo, led by Drake Maye’s breakout, and a defense that forced three turnovers. They face a Saints squad that leans on Spencer Rattler’s efficiency and a feisty, turnover-hungry unit, aiming to keep the game ugly and swing momentum with mistakes. Injuries haunt the Patriots’ secondary, notably Christian Gonzalez, which could invite a more conservative plan from New England. The all-time series lead sits with the Patriots (10-6), though a 34-0 loss in the last meeting underscores the risk of any overconfidence. Fantasy focal points include Maye’s continued growth, Diggs’ high-volume presence in this broader context, and Marcus Jones’ chances to cash in on opportunistic plays.

Ultimately, this is a defensive-duel flavored by young quarterback development. Saints fans will push Rattler to sustain efficient drives while trying to force turnovers on a Patriots squad short-handed in the secondary. For fantasy bettors, watch Maye’s rhythm against a disciplined Saints defense, the Saints’ ability to exploit any safety gaps, and Jones’ ceiling as a takeaway catalyst in a pivotal Week 6 contest.