Buffalo faces a short-week showdown in Week 2 at the Meadowlands, aiming to exploit New York’s cover on the boundary and corral Justin Fields’ rushing ability. The plan centers on attacking Brandon Stephens with route variety and motion to test the Jets’ depth, while keeping a tight lid on Fields’ legs. Ed Oliver’s absence heightens the challenge on defense, making disciplined gap control crucial as Buffalo seeks rhythm in a compressed schedule.

Two-on-two, the Bills must shift the passing game into gear and pressure the Jets with timely blitzes and smart containment. If Buffalo can establish a steady passing tempo and limit Fields’ scrambles, a road win becomes a realistic outcome despite the quick turnaround.

New Orleans faces a tough test as Spencer Rattler and a battered offense host San Francisco. With Taysom Hill, Foster Moreau, Trevor Penning, and potentially Taliese Fuaga sidelined, the Saints must push a more efficient passing game and smarter play design to avoid an 0-2 start.

For fantasy managers, focus on Rashid Shaheed, Chris Olave, and Alvin Kamara as the trio most likely to produce targets and yards if the Saints unlock play-action and get the ball into space. San Francisco’s defense remains elite up front and in coverage, so protection and precision from Kellen Moore and Rattler will be pivotal for any redemption day in week 2.

Miami's right side is in flux as Austin Jackson lands on IR and James Daniels joins him, forcing a reshaped O-line for at least four games. Borom steps in at right tackle with Kion Smith sliding to right guard; Strange, Brunskill or Lamm may inherit later opportunities. Waller remains in the lineup with a two-TE look, and Wilson Jr. plus Patterson get practice-squad elevations to stay ready. Cornell Armstrong moves up to fifth cornerback as Bonner sits, while Wright is doubtful and Waller stays active.

Depth and tempo become the x-factors: the Dolphins will lean on internal depth, situational protection schemes, and occasional run-game adjustments against a brutal early schedule (Patriots, Bills, Jets, Panthers). The earliest Jackson or Daniels could return is Week 6 vs Chargers, giving Miami a light at the end of the tunnel as Eichenberg works off PUP. Fantasy angles hinge on who seizes the opportunistic reps along the line and how the TE and RB options are deployed in the shift.