Drafting rookie running backs can be a game changer in fantasy football, especially in 2025. Emerging talents like Zach Evans and Ty'Son Williams are poised to make a significant impact, with Evans showcasing explosive speed and agility, making him a prime target for fantasy managers. Meanwhile, Williams has demonstrated impressive versatility, proving to be a dual-threat option that can catch passes as well as run between the tackles.

Players such as De'Von Achane and La'Darius Henderson also rank high on the sleeper list. Achane's elusiveness and speed present big-play potential, while Henderson’s work ethic and ability to find holes in the offensive line make him a solid sleeper pick. As teams continue to adapt to a more pass-heavy league, these rookie running backs could provide valuable depth and unexpected points in fantasy leagues.