Week 2 injuries reshape fantasy NFL rosters. Burrow's toe surgery outs him for months; Browning starts, elevating Chase's and Higgins' ceiling only if Cincinnati stabilizes at QB. Reed's 6-8 week absence widens Packers targets to Wicks, Doubs, and Kraft while Love powers the offense. Ekeler's season-ending injury opens Croskey-Merritt as Washington’s lead back, with Jones’ hamstring risk looming. Fields' concussion creates Jets QB uncertainty, boosting Tyrod Taylor as a streamer. Week 3 brings more volatility as backfields and pass-catching duties shift to fill the gaps.

Jets fell 30-10 to the Bills as the offense never found rhythm, Justin Fields left with a concussion, and Garrett Wilson struggled to get going. The Jets’ new regime faces a tough early test against a Buffalo squad that dictated terms in all three phases.

Buffalo dominated the line, with James Cook ripping off chunks and the defense stifling the Jets’ attempts. Aaron Glenn took responsibility, signaling the need for quick tweaks. For fantasy managers, Fields’ health, Wilson’s volume, and Cook’s workload are the levers to watch as New York regroup in a tough stretch.

Fantasy takeaway: monitor Fields’ status, Wilson’s target share, and Cook’s carry count. If Fields misses time, Tyrod Taylor could alter the QB landscape and overall Jets upside in the near term.

Buffalo’s defense answered Week 1 doubts with a stifling showing against the Jets, holding New York to 154 total yards and 10 points. Breece Hall was bottled to 29 yards on 10 carries, while Justin Fields added just 27 rushing yards on a key scramble. The Jets’ passing game also stagnated, with Garrett Wilson limited to 50 receiving yards on four grabs.

Rookie reinforcements carried the load on Buffalo’s line: Deone Walker, TJ Sanders, Zion Logue, and DaQuan Jones stepped up with solid snaps as Ed Oliver and Taron Johnson were sidelined. Joey Bosa wrecked the pocket with two forced fumbles, a sack, six pressures, and two hits, helping Buffalo post four sacks and 23 pressures overall. Buffalo hosts Miami next, aiming to keep building defensive cohesion.

In a Week 2 reversion to form, Buffalo proved it can adapt quickly, leveraging front-seven depth and a relentless rush to stabilize after Week 1 turmoil. The matchup against the Dolphins will test whether this developing unit can sustain pressure on a high-caliber offense on a short week.

Week 2 fantasy lineups hinge on clear roles and favorable matchups. Garrett Wilson should soak up targets against Buffalo, while Travis Etienne Jr. benefits from Tank Bigsby’s trade leaving him with extra touches in Jacksonville. Calvin Ridley’s volume remains solid despite a tougher matchup, and D.J. Moore projects steady targets facing Detroit. Marquise Brown could command looks with Kansas City short on WR depth, creating upside as a viable start in many leagues.

The article also highlights a powerful start/sit tool to compare up to four players, plus a snapshot of popular Week 2 searches. It emphasizes leveraging weekly projections, matchup data, and scoring formats to set optimal lineups for the 2025 season.

Buffalo aims to attack New York’s secondary with a precision-heavy passing attack, leveraging Josh Allen’s prime form and Joe Brady’s scheme to maximize yards-after-catch and red-zone efficiency. A fast, clean start in Week 2 would push the Bills to 2-0 and force the Jets into rare mistakes in a divisional bout.

The Bills’ defense seeks a repeat performance against a run-first, mobile offense, even with Ed Oliver sidelined by an ankle injury. Rookie T.J. Sanders steps into a bigger role as Buffalo pressures Zach Wilson and neutralizes the Jets’ ground game, while Buffalo fights for balance and control of pace to dictate the tempo at MetLife.

Key narratives center on Allen’s ability to exploit a vulnerable Jets secondary, the Bills’ offensive efficiency under Brady, and the defense’s capacity to replicate a plan that stifles a multi-faceted attack. If Buffalo can execute with discipline, convert in the red zone, and limit big plays, the Week 2 win can reinforce the AFC East message.