Week 1 fantasy pivots center on Wilson, Moore and Harrison Jr. Wilson faces a stout Steelers secondary and projects as a low-end WR3 in most formats. Moore steps into a Bears’ primary role with favorable Vikings math, making him a solid WR2 start in Week 1. Harrison Jr. carries considerable upside in Week 1 with a favorable outside matchup, likely a strong WR3/WR2 in PPR. Also notes early-season usage for Tyrone Tracy Jr., Braelon Allen, Dobbins and Chubb to shape lineups.

Lineup guidance stresses upside and risk: lean into the studs but respect Week 1 game scripts that can tilt toward the run. The article offers concrete rankings, matchup notes, and quick reads to help managers decide who to start, pivot, or bench in 12-team leagues as the season begins.