Ed Oliver's ankle injury could tilt Week 2 in Buffalo's favor, forcing the Bills to lean on a thinner interior against a Jets rushing attack. New York aims to keep the game plan simple and punishing on the ground, with Fields carving running lanes behind a solid, cohesive line.

Four Jets stars must shine: Sauce Gardner shadows Buffalo's top options, Quinnen Williams thrives at three-tech, Bree Hall runs decisively, and Garrett Wilson remains the trusted target. Justin Fields' efficient Week 1 showing adds a layer of faith that the Jets can sustain a run-first approach while keeping passing efficient. Buffalo counterpunches with a receiver-by-committee approach led by Keon Coleman and Josh Allen spreading the ball around.

As Buffalo looks to prove it can stop the run, New York's formula hinges on simplicity on both sides of the ball and a disciplined run game that tests a potentially vulnerable defensive front. The matchup holds fantasy intrigue at every key position, especially for those betting on Jets-stacked concepts or Bills breakout targets in a still-developing offensive landscape.