The Buccaneers lose Cody Mauch for the year to a knee injury in Week 2 versus Atlanta, and Luke Goedeke exits the same game, leaving an already thin offensive line to absorb a massive hit. A revamped five (Graham Barton, Elijah Klein, Ben Bredeson, Michael Jordan, Charlie Heck) must hold up in Week 3 against a Jets front that can wreck protections. Tristan Wirfs is approaching a return, but timing remains uncertain, amplifying fantasy angles around Tampa Bay’s line and skill players.

Keon Coleman has flashed big-play upside for Buffalo in 2025, posting Week 1 numbers that underscored his role as Josh Allen’s premier deep threat. A quieter Week 2 tempered expectations, but Thursday’s date with the Dolphins could unleash another boom game if Buffalo leans on the passing attack. Coleman remains a high-end WR3/Flex in 10-12 team leagues, offering weekly upside when the Bills air it out.

Miami’s defense has bent but not broken on WRs early, so Coleman’s ceiling hinges on volume and red-zone looks. If Buffalo pushes the ball downfield to chase points, Coleman could again hit double-digit targets and multiple big plays, making him a compelling fantasy option in the right matchups.

Khalil Shakir's Week 3 fantasy outlook isn’t as clear as last season. Buffalo is leaning on the ground game early, narrowing Shakir’s targets while Keon Coleman emerges as Josh Allen’s top option. The Dolphins present a better matchup, but Shakir remains a high-variance, fringe WR3/Flex option who needs a target surge to pay off. Expect a week defined by volume and game script more than clear volume, making him a riskier play in shallow formats.

Shakir flashed in Week 1 but was quiet in Week 2 as Buffalo leaned on the rushing attack. Coleman’s ascent further compresses Shakir’s ceiling, though a shootout could still spark a big day if Buffalo pushes pace or finds success through the air. Treat Shakir as a boom/bust option in Week 3, with Coleman ahead for steadier fantasy returns.