Danielle Hunter lands at No. 25 on the NFL Top 100 as the Week 15 road test for Arizona’s defense against Houston looms large, a matchup that could shape DFS and season-long decisions. Arizona slots Budda Baker, Trey McBride and Josh Sweat on the Top 100 roster this year, underscoring a mix of playmakers on offense and defense. The Cardinals’ 2025 schedule features a parade of top opponents, including Hendrickson, Warner, Stingley, Wirfs, Kittle, Nacua, Jacobs, Lamb and Parsons, crafting a rich fantasy-mue for edge-rushes and matchups across the board. Johnson Jr. and Williams will have a stern test against Hunter’s edge, while Hunter’s 12-sack bounce-back year signals a pivotal Week 15 tilt that could swing defensive DFS values.

The article also highlights fellow Cardinals on the Top 100—McBride and Baker—adding nuance to Arizona’s fantasy storyline as the club navigates a calendar packed with premier playmakers. Across the 2025 slate, fantasy owners should map Hunter’s peak weeks against top offenses and leverage Baker’s coverage range, McBride’s tight-end upside, and Sweat’s ability to pressure even elite quarterbacks. These factors, plus the Cardinals’ testing schedule, shape weekly lineup considerations and weekly DFS pivots.

Saints final four roster spots hinge on RB depth, linebacker mix, and edge rotation after Devaughn Vele’s trade reshapes the WR room. Devin Neal and Clyde Edwards-Helaire lead a tight RB contest, while Luke Fortner and Shane Lemieux clash for the ninth OL spot. Jonathan Bullard, Fadil Diggs, Jonah Williams, D'Marco Jackson, Isaiah Stalbird, and Nephi Sewell headline the edge/LB group, with Cedrick Wilson Jr. pushed toward the practice squad by the Vele move. Saturday’s dress rehearsal vs. Denver will seal the fate.

Arizona rookie Hayden Conner exited the Cardinals’ Saturday tune-up with a knee injury after just three plays, drawing quick questions about interior-line depth and 53-man roster implications. Conner had been cross-training at center as Jon Gaines, hampered by a thumb issue, has struggled to snap. A serious knee issue could push the Cardinals to lean more on reserve linemen as they decide who travels to Week 1. Cramping issues were noted for a couple players who later returned. The 27-7 loss to Denver highlighted how precarious the O-line could be if Conner is sidelined.

Convincing debate for fantasy managers centers on how Conner’s status could shift snap counts and blocking schemes, especially if Gaines can’t snap consistently. With the Cardinals juggling roster spots, any setback could ripple to run-game efficiency and short-yardage packages early in the season, making depth pieces and practice squad candidates more worth monitoring than usual in late August.