Arizona’s 22-21 home loss to Tennessee ranks as the franchise’s worst in Arizona history, a collapse from a 21-6 fourth-quarter lead. A late sequence featuring Emari Demercado’s nullified TD, Dadrian Taylor-Demerson’s pick that caromed into a Titans TD, and a 38-yard Ridley grab set up Joey Slye’s game-winning 29-yard field goal as time expired.

The loss exposes glaring mental-m toughness issues, with Calais Campbell urging a true fighter response and coach Jonathan Gannon acknowledging this would rigorously test the team’s resolve. For fantasy owners, the Демercado miscue looms large, while Ridley’s big play potential remains a silver lining as Tennessee survives a stumble-prone night.

Titans erased a 21-3 deficit to stun the Cardinals 22-21 in Week 5, fuelled by Arizona miscues and a late Tennessee surge. Emari Demercado’s wide-open TD fumble sparked the rally, a Dadrion Taylor-Demerson turnover turned into a Titans TD with Tyler Lockett cashing in, and Cam Ward then orchestrated a 71-yard march that set up Joey Slye’s 29-yard game-winner. Tennessee’s first win since 2024 capped a wild comeback.

Ward, the No. 1 overall pick, looked poised on the late drive, while Kyler Murray couldn’t close it out for Arizona. The chaotic sequence underscored Tennessee’s resilience and could shift fantasy outlooks as Ward gains a clearer hold on the offense and Slye becomes a trusted kicking option.

Titans travel to Arizona seeking their first win as Cam Ward’s rookie season has stalled Tennessee’s offense, already blanked once this year. Kyler Murray and a Cardinals squad at 2-2 are expected to test Tennessee’s secondary, while Arizona’s attack aims to strike early and keep the pressure on. The desert showdown carries heavy fantasy implications: Ward must break the drought, Murray’s rushing floor adds upside, and special-teams or breakout plays from Chimere Dike or Joey Slye could swing a tight game.

Experts lean toward Arizona, with several predictions favoring a Cardinals win and a modest Titans scoring showing. For fantasy managers, the focus is on Ward’s development, Murray’s ceiling in a favorable matchup, and potential value from Arizona and Tennessee ancillary pieces if the offenses finally click or a defensive-styled game drives field-position scoring. Stay tuned for how the kickers and kickoffs may shape the scoring table in a low-total affair.