Colts vs. Raiders in Lucas Oil Stadium shapes up as a fantasy-friendly test: Indy sits 3-1 atop the AFC South while Vegas looks to rebound from a tight loss. Ashton Jeanty’s Week 4 breakout boosts Raiders’ backfield optimism and Brock Bowers enters Indy’s targets in the matchup’s narrative. Injury notes for Mayer, Pierce and others could tilt snap shares and opportunity as the game unfolds.

Odds tilt Indy, but only by a hair, with a -6.5 spread and a 47.5 total. Rogers-like turnover pressure on Geno Smith and Jones’ ball security will be pivotal; Jeanty and Indy’s improved run-pass mix should shape DFS value and weekly bets.

Las Vegas hosts Chicago in Week 4 with injury notes shaping fantasy value. Brock Bowers is a full participant and looks set to play, while Michael Mayer is out, thinning the Raiders' tight-end corps. Jeremy Chinn's return strengthens the Raiders' secondary, and Decamerion Richardson is limited, testing depth at cornerback.

Chicago arrives with Edwards out and Jarrett out on the defensive line, Colston Loveland questionable, Darnell Wright out, Kyler Gordon questionable, and Jaylon Jones and Cole Kmet among remaining targets to monitor. D'Andre Swift and D’Marco Jackson carry question marks for the Bears. The game will hinge on depth players stepping up and how the new coaches game-plan for the Raiders at Allegiant Stadium.

Caleb Williams' breakout against Dallas fuels cautious Bears optimism as they head to Las Vegas, with Williams' blend of arm talent and rushing ability giving fantasy managers a clear high ceiling this week.

Geno Smith directs a Raiders attack that can pop for big plays but remains volatile, setting up a potentially fantasy-friendly shootout if Chicago's injury-riddled defense can’t limit the aerial attack.

Odds tilt Bears -1.5 with a 47.5 total per DraftKings; lines and props are live as Week 4 unfolds, and NBC’s betting chatter plus waiver targets shape the DFS angle for quarterbacks and tight ends.