Denver opens 2025 with a charged Mile High debut against the Titans. Bo Nix leads a revamped attack featuring R.J. Harvey and J.K. Dobbins in a wide zone run game, while Evan Engram and Troy Franklin provide big-play potential. The defense, led by Pat Surtain II, aims to press Cam Ward and force sacks and turnovers while depth players must fill for the injured Dre Greenlaw and Malcolm Roach. Week 1 feel-out becomes a test of explosiveness, penalties, and situational football.