Denver leans on inside linebacker depth for Week 1, calling up Levelle Bailey, Jordan Turner, and Garret Wallow from the practice squad to backstop possible injuries to Alex Singleton and Dre Greenlaw’s return. The club plans to manage pitch counts and rotate younger players as a prudent Week 1 approach, with up to two practice squad elevations possible for game day against the Titans at Empower Field. Expect Adam Prentice to support those elevations as the team weighs veteran rehab with fresh legs in a season opener.

Injury management and roster flexibility drive Denver’s Week 1 strategy. Singleton and Greenlaw are monitored closely as Denver weighs smart usage, while the practice squad trio provides insurance and potential breakout depth. The Titans visit Mile High on Sept. 7, and the Broncos will test how their LB depth handles a fast, physical Week 1 test while preserving health for a longer playoff push.

Broncos set up a 17-player practice-squad path for Week 1. Sam Ehlinger lands as QB3 on the practice squad, choosing Denver over other rosters to stay in Sean Payton’s quarterback room. No running backs land on the practice squad, leaving J.K. Dobbins, RJ Harvey, Tyler Badie and Jaleel McLaughlin on the 53-man roster. Adam Prentice is the visible fullback on the practice squad with trip-waiver elevation flexibility. All seven 2025 draftees are under contract, Caleb Lohner among them. A 17th international spot goes to Patrick Murtagh, adding a developmental tight end.

The Broncos also trimmed undrafted WRs, signing A.T. Perry and Michael Bandy while Jerjuan Newton, Kyrese Rowan and others remained free agents. Levelle Bailey and Calvin Throckmorton were notable return-cuts, though Throckmorton can be recalled from the practice squad. Denver added Jordan Turner and Garret Wallow back to the practice group and kept Karene Reid on the active roster, signaling a flexible, development-heavy approach for 2025.

The Denver Broncos placed Nick Gargiulo on season-ending injured reserve after a knee injury in Saturday night’s preseason win against Arizona. Gargiulo, a 6-5, 310-pound seventh-round pick from South Carolina, was vying for a swing guard/center role before the injury ends his 2025 season prior to the 53-man roster. To fill Gargiulo’s spot on the 91-man offseason roster, Denver signed fullback Adam Prentice, a move aimed at bolstering blocking and depth behind Michael Burton and Nate Adkins, who are dealing with injuries.

Broncos injury news also includes rookie corner Joshua Pickett with a wrist/thumb issue and outside linebacker Garret Wallow leaving the game with an ankle injury. Burton (hamstring) and Adkins (ankle) were limited as the team continues to piece together its Week 1 picture. Prentice’s addition signals a depth-forward approach at the fullback/linebacker mix rather than a sweeping lineup shift, as Denver navigates roster decisions ahead of the regular season.

Fantasy managers should monitor how Denver reshapes interior-line rotation and how Prentice is used in goal-line and short-yardage plays, especially with Burton and Adkins sidelined. Gargiulo’s IR clears roster-space chatter, but the Broncos’ move to add Prentice underscores a practical, depth-conscious plan rather than a dramatic positional overhaul as the team approaches Week 1.