Five bold Week 2 predictions for Denver vs. Indianapolis shape a fantasy-friendly path: a 200+-yard rushing onslaught with one back eclipsing 100 yards; Bo Nix climbs to 70% completions with 200 passing yards, a touchdown and no interceptions, while the offense emphasizes the run early. Denver’s defense eyes a six-sack performance from different players, including a secondary contributor, plus three takeaways. Jeremy Crawshaw bumps to a 49.5-yard punt average on a handful of tries, while Payton’s plan leans into ball control and field-position leverage.

The Colts’ run defense is vulnerable, even as their pass defense shines; if Denver can sustain the ground game, the game plan should unlock better efficiency for Nix and keep the chains moving. The piece uses a Giants scenario to illustrate pressure-induced turnovers, underscoring how the Broncos’ defense and special teams could swing outcomes in a close contest. For fantasy bettors, focus on the running back workload, Nix’s efficiency, sack distribution, and Crawshaw’s punting windows.

Bo Nix and teammates from the Broncos turned a rain-soaked Colorado night into a subtle fantasy signal, jamming with Riley Green at Red Rocks and gifting him a Broncos jersey. The moment highlights a tightly knit locker room vibe and signals depth in the QB room as Denver heads toward Week 1 with Tennessee on the horizon.

Off the field, Nix’s visibility pairs with a familiar arms-length QB group in Stidham and Ehlinger, while Wil Lutz, Mike McGlinchey, and Brandon Jones anchor the周 offense and defense. For fantasy, keep an eye on how this chemistry translates to on-field consistency, QB competition dynamics, and how Lutz’s leg and Denver’s run game could shape weekly scoring.

The Broncos’ Year 2025 opener against the Titans could set the tone for notable value in a crowded QB room and a resilient special-teams unit, where off-field camaraderie and leadership often foreshadow real on-field upside.