Saints host the Giants in Week 5 chasing their first win. The run game has carried them, but the aerial attack must spark with Spencer Rattler, while Olave and Shaheed must threaten downfield.

Giants' edge trio Burns, Thibodeaux, and Carter provides heavy pressure; Adebo, Flott and Phillips anchor the secondary. If Nubin sits, Belton steps in to test the Saints on early downs.

O-line must hold and Kamara must play a bigger receiving role to free up Olave and Shaheed.

New Orleans received encouraging injury news as Taliese Fuaga moved from limited to full participation, hinting at a probable return to the starting lineup against Buffalo. The Saints’ other statuses remained largely unchanged: Chase Young still limited by a calf, Dillon Radunz toe-out, while Treys Palmer (hamstring) and Devaughn Vele (hip) were limited. Cameron Jordan and Trevor Penning practiced without restriction. For Buffalo, Ed Oliver and Matt Milano remained out with ankle and pectoral injuries, Spencer Brown calf, and AJ Epenesa limited. Final Friday updates will define the game-day depth chart and fantasy rotations.

Fantasy angles center on Fuaga’s return stabilizing New Orleans’ line in a matchup that could unlock more run and play-action efficiency. The Bills’ sidelined stars on defense could open interior running lanes, while Buffalo’s on-field injuries may press the Saints to lean on their BPA (best plays available) options behind the line. In Billsville, Oliver and Milano out questions how the defense will generate pressure and maintain gap discipline, especially with a limited Epenesa and Brown’s status still murky.