Denver pairs Alex Singleton and Dre Greenlaw in the middle to anchor a defense rebuilt after injury setbacks, opening against the Titans and Cam Ward. Singleton’s communication and leadership, wearing the green dot, should help the run and pass fits, while Greenlaw’s burst and Mike Tyson-style physicality bring complementary heat. With both coming off major injuries, expect a cautious but pivotal minutes plan as the season begins.

The matchup against Ward offers a stern early test for a Broncos unit betting on a steady, versatile front seven. Fantasy managers should monitor workload ramps and potential tackle volume from the two veterans as Denver aims for a durable, long-haul blueprint in a newly anchored defense.