Ja'Quan McMillian's journey with the Denver Broncos has been a testament to perseverance and growth. Initially signed as an undrafted free agent, McMillian's collegiate career at East Carolina showcased his potential, highlighted by impressive stats including 12 interceptions and 28 pass deflections over three seasons.

In his first season, he primarily spent time on the practice squad, but a strong performance in the 2022 season finale earned him a spot on the 2023 roster. By 2024, he secured the slot cornerback position with notable contributions, including a standout pick-six against the Cleveland Browns. His trajectory reflects both individual skill development and adaptability within a competitive defensive scheme.