Week 2 DFS spotlight centers on five RB matchups: Gibbs vs Bears, McCaffrey vs Saints, Conner vs Panthers, Hall vs Bills, Williams vs Cowboys. The focus is on game-script independent backs who can reach 15-20 touches regardless, a rarity in today’s NFL.

The Lions look to rebound at home while Chicago’s run defense isn’t as stout as last year. Arizona and San Francisco lean on their respective lead backs, with New York’s duo in a favorable grind. These spots fuel DFS lineups, season-long builds, and prop bets alike.