Dreeze Greenlaw and Nate Adkins were the Broncos’ two DNPs on the 2025 injury report, with Greenlaw nursing a quad issue and Adkins sidelined by an ankle. Denver is taking a thoughtful, long-horizon approach to Greenlaw, planning to be smart and conservative early in the season. If Greenlaw cannot go, Justin Strnad would slide in opposite Alex Singleton, a shift that could influence Titans’ Week 1 game plan.

Denver’s other listed full participants—Nik Bonitto and Marvin Mims—signal the defensive depth and weapons they’ll lean on early. Payton’s stance on injuries emphasizes mandatory reporting over speculation, a stance that could keep fantasy managers in the dark until later in the week while the Broncos monitor practice reps and roster moves for Sunday.