Denver opens against Tennessee with a Week 1 milestone emphasis. Bo Nix targets three passing TDs in his first 18 starts and 400 completions by then, while Engram, Sutton, and Surtain II chase career-defining marks in the debut. Nik Bonitto looks for two sacks to join a small Broncos club, creating a favorable fantasy angle in Payton's first Week 1 as head coach.

Engram’s push toward 500 catches could boost Broncos volume; Sutton could climb past Emmanuel Sanders in team history with modest yardage, and Surtain II eyes a pick-six milestone. Denver’s defense and sack upside versus the Titans adds another layer for DFS and season-long projections.