Jacksonville heads into Week 5 against Kansas City with optimism that Liam Coen’s offense can unlock Trevor Lawrence and the Jaguars’ arsenal. Lawrence could post his best fantasy day of the season as Jacksonville tries to keep pace with Mahomes and the Chiefs. BTJ has shown progress and could seize the moment against a middling KC secondary, while ETN continues to be the steady fantasy engine. The matchup hints at a potential shootout that could redefine Jacksonville’s fantasy ceiling in 2025.

Expect Lawrence to lean on downfield threats if the protection holds, BTJ to turn a favorable matchup into a multi-catch day, and ETN to once again smash double-digit fantasy points. If Coen’s scheme clicks, Week 5 could mark a turning point for fantasy managers riding the Jaguars’ offense.

Chiefs show momentum with Worthy back, lifting KC’s offense and EPA after a rough early stretch. Jaguars counter with a defense elite in takeaways and a home-field edge that keeps them square in the fantasy spotlight. The game hinges on turnover battles and which unit can sustain drive efficiency while limiting mistakes. Brian Thomas Jr. remains under 56.5 receiving yards, presenting a potential fade play if Jacksonville leans on other weapons.

Travis Etienne is projected by SportsLine's ML model to exceed 70 rushing yards against Kansas City, with a +110 price at FanDuel. The Jaguars sit at 3-1, and Etienne has cleared 70 rushing yards in 3 of 4 games this season, aided by Jacksonville's prolific ground attack. The model also flags Tyquan Thornton as an anytime TD scorer (+400) for Kansas City and Brian Thomas Jr. as a +185 TD scorer for Jacksonville, with Thomas slated for solid receiving work.

These Week 5 projections frame a value-packed slate around cross-team bets, highlighting Etienne's 71-yard projection, Thornton's scoring upside, and Thomas Jr.’s receiving role. Promotions from Caesars and DraftKings are noted alongside FanDuel’s +110 on Etienne, underscoring compelling leverage in a Chiefs-Jaguars showdown.

Week 5 Monday Night Football features Kansas City visiting Jacksonville in a likely high-scoring showdown (Total 45.5, KC -3.5). Xavier Worthy returns to a clearer target role for Kansas City with Rashee Rice suspended, making him a solid WR2 option as the Chiefs lean on Mahomes, Kelce, and Etienne remains a steady RB2 for Jacksonville.

Key decision points center on whether Brenton Strange can sustain TE2 value against KC, how Brian Thomas Jr. grades out vs Trent McDuffie, and if Worthy edges out Thomas in fantasy lines. KC’s defense and Butker look like safe plays, while Hunter is usually a sit. Build around the obvious stars and temper expectations for some ancillary pieces in Week 5.