Week 2 starts with Kyren Williams as the Rams’ clear RB1, a big-volume play against Tennessee that should anchor many lineups. Lawrence and Burrow headline top QB options, with Nacua and Ridley providing elite target shares and Adams delivering steady floors. Etienne and Strange present strong midrange options, while a raft of wideouts and tight ends fill the rest of the board.

Smart Week 2 fades include rookie Cam Ward against a stingy Rams secondary, with Brenton Strange and Khalil Shakir offering safer floors in different formats. The guide maps matchup-driven starts, injuries, and upside calls to help you optimize rosters and avoid pitfalls.

Week 2 pits the Cincinnati Bengals against the Jacksonville Jaguars in a clash that could hinge on run-first balance and big-play ability. Cincinnati eyes a sharper defense and Burrow-led offense, while Jacksonville leans on Lawrence’s arm and Etienne’s workload to accelerate the attack. Expect a high-scoring affair, with McPherson providing late-game scoring opportunities for the Bengals if the game stays tight.

Fantasy angles center on Etienne and Brian Thomas Jr. for Jacksonville, Burrow and McPherson for Cincinnati, and the favorable matchups that could unlock turnover-driven points for Cincinnati’s defense. The game sets up for a strategic, back-and-forth battle where early scripts may dictate the ceiling for several role players.

Christian Kirk will miss a second straight Texans game with a hamstring, leaving Nico Collins, Xavier Hutchinson and Justin Watson to pace Monday night’s attack against Tampa Bay. Braxton Berrios is out too, and rookies Jayden Higgins and Jaylin Noel could see extra targets as Tank Dell’s 2025 absence looms large.

Weeks 3 vs Jacksonville could finally bring Kirk back, a reunion with his former team that would reshape Houston’s target share and lift the value of the top three receivers and the rookies stepping in now.