Week 2 starts with Kyren Williams as the Rams’ clear RB1, a big-volume play against Tennessee that should anchor many lineups. Lawrence and Burrow headline top QB options, with Nacua and Ridley providing elite target shares and Adams delivering steady floors. Etienne and Strange present strong midrange options, while a raft of wideouts and tight ends fill the rest of the board.

Smart Week 2 fades include rookie Cam Ward against a stingy Rams secondary, with Brenton Strange and Khalil Shakir offering safer floors in different formats. The guide maps matchup-driven starts, injuries, and upside calls to help you optimize rosters and avoid pitfalls.

Week 2 pits the Cincinnati Bengals against the Jacksonville Jaguars in a clash that could hinge on run-first balance and big-play ability. Cincinnati eyes a sharper defense and Burrow-led offense, while Jacksonville leans on Lawrence’s arm and Etienne’s workload to accelerate the attack. Expect a high-scoring affair, with McPherson providing late-game scoring opportunities for the Bengals if the game stays tight.

Fantasy angles center on Etienne and Brian Thomas Jr. for Jacksonville, Burrow and McPherson for Cincinnati, and the favorable matchups that could unlock turnover-driven points for Cincinnati’s defense. The game sets up for a strategic, back-and-forth battle where early scripts may dictate the ceiling for several role players.