Week 1 features the NFC West’s fiercest clash as the 49ers visit Seattle. San Francisco arrives with a healthy, star-studded offense led by Purdy and friends McCaffrey, Aiyuk, and Kittle, aiming to remind the league their championship window is still wide open. Seattle counters with a revamped attack under a new scheme and Darnold at the helm, with Jaxon Smith-Njigba ready to spark the offense.

Expect a physical, sometimes messy opening half, then SF’s depth, coaching edge, and playmakers pull away. Smith-Njigba could provide the Seahawks a meaningful spark with 70+ receiving yards and a TD, while Purdy, McCaffrey, and Kittle anchor a late surge for the visitors.

San Francisco stands at an inflection point in 2025, leaning on a rising core as the window on glorious runs tightens. Purdy carries the weight of a five-year, $265 million deal and must elevate a new supporting cast to keep the offense humming. Bosa remains elite, but a younger line around him requires more dominance to keep the defense rolling. Pearsall needs a breakout year as the No. 1 option, while Shanahan’s job security adds a pressure layer on every decision.

As the 49ers navigate this crossroads, fantasy managers should watch Purdy’s development, Pearsall’s opportunity window, and the defense’s ability to adapt with rookies ready to contribute. The blend of veteran expectations and a growing young backbone signals a potential regroup-and-rise season rather than a simple continuation of the ascent.

2025 fantasy drafts are here and the chatter centers on how Detroit’s offense might shift with Ben Johnson gone, plus which players are rising fast. Jameson Williams stands out as a prime breakout candidate for 2025, with two years of team control and a path to increased targets in Detroit’s revamped attack. The SportsLine model highlights sleepers like Brock Purdy, breakouts like Travis Hunter, and potential busts like Jaylen Waddle, offering ranked cheat sheets for all formats.

Other notable themes: Trevor Lawrence could boost Jacksonville’s passing game under Liam Coen, Amon-Ra St. Brown remains a safe anchor in DET, and Purdy could outperform early-round QBs according to the model. The piece also flags Williams as a potential challenger to St. Brown for Detroit’s top target share, while outlining a structured approach for PPR vs non-PPR leagues.

Packers add Matthew Golden and Savion Williams, and with Christian Watson sidelined, Golden is pegged to step in alongside Jordan Love in a high-powered offense.

SportsLine's 2025 fantasy model projects Brock Purdy as a sleeper QB around seventh-round ADP, while Trevor Lawrence and C.J. Stroud are highlighted in notable breakout or bust conversations, respectively, with Mahomes, A.J. Brown, Tyreek Hill and DeVonta Smith in the top tier discussions.

Busts include Garrett Wilson in a Jets’ QB carousel context, and the piece emphasizes using dynamic rankings and cheat sheets for late-draft leverage, sleepers, breakouts and fades.

Target the Packers’ new WR room with an eye on Love’s timing and the added weapons, and lean on the model’s sleepers and breakouts to shape a smarter 2025 draft plan.