Pearsall’s rookie year was crushed by a gunshot and a four‑game layoff, yet he returns with 11 receptions for 400 yards and three touchdowns, flashing big‑play potential for SF. Williams’ praise of Pearsall’s grace and leadership adds a locker‑room boost, hinting at a larger role in a crowded 49ers passing game this season.

The resilience story offers fantasy upside: a speed threat who could push into a bigger target share if health holds and usage grows. In SF’s dynamic offense, Pearsall's ceiling is real, though competition remains and a secure role will determine weekly fantasy value.

Week 1 features the NFC West’s fiercest clash as the 49ers visit Seattle. San Francisco arrives with a healthy, star-studded offense led by Purdy and friends McCaffrey, Aiyuk, and Kittle, aiming to remind the league their championship window is still wide open. Seattle counters with a revamped attack under a new scheme and Darnold at the helm, with Jaxon Smith-Njigba ready to spark the offense.

Expect a physical, sometimes messy opening half, then SF’s depth, coaching edge, and playmakers pull away. Smith-Njigba could provide the Seahawks a meaningful spark with 70+ receiving yards and a TD, while Purdy, McCaffrey, and Kittle anchor a late surge for the visitors.

Jauan Jennings returns to 49ers practice after calf injury and a suspected contract holdout, setting the stage for an unsettled Week 1 at Seattle. His reintroduction comes with questions about speed, route timing, and overall conditioning after limited camp time. The SF offense may lean on Deebo Samuel, Brandon Aiyuk, and George Kittle early, while Jennings works to regain his role and trust in the offense.

Historical holdouts suggest a cautious ramp, and the calf risk adds another layer of risk for fantasy managers. If Jennings isn’t fully back by Week 1, Seattle’s defense could clamp down, making Jennings a risky Week 1 option with potential to trend up as he proves he’s fully operational in the following weeks.

Parsons to Green Bay reshapes the NFC power structure, elevating the Packers while the Rams grapple with Stafford’s back issue. Love’s development and SF’s weaponry keep the conference competitive, with Detroit, Tampa Bay, and Atlanta lurking for playoff spots as the season opens.