San Francisco’s preseason opener vs. Denver yielded a 30-9 setback, but the real headlines were the cluster of injuries and how quickly the 49ers’ depth will be tested. Key youngsters exited (Bethune, Sigle, Abdullah, Beal Jr.) with a mix of ankle, knee, rib, and groin issues, while Western Kentucky rookie Upton Stout and Mykel Williams joined the casualty list. Coach Kyle Shanahan emphasized cautious handling, with timelines pegged to next week’s joint practice against the Raiders. San Francisco hopes several returning players (Cowing, Renardo Green) clear workouts soon to rejoin practices. The situation will shape practice reps and potential Week 1 depth, especially at linebacker, safety and edge. Fans will be watching how quickly the squad recovers and who steps up in the interim.

The San Francisco 49ers face a pivotal season as they assess their roster with several players on the brink of proving their worth. The pressure is particularly on defensive end Robert Beal Jr., who had a disappointing year and must step up to secure his place. Other players in similar situations include offensive tackles Colton McKivitz and Jaylon Moore, as well as tight end Ross Dwelley. The team is also looking at quarterback Brock Purdy to solidify his role. The stakes are high for these players to perform or risk being replaced.

Joshua Dobbs has been named the starting quarterback for the San Francisco 49ers in their season finale against the Arizona Cardinals, stepping in for the injured Brock Purdy. Coach Kyle Shanahan made the announcement, citing Dobbs' mobility as a key factor given the team's struggling offensive line, which will feature several backup players.

Despite the 49ers' disappointing 6-10 season, Dobbs' experience, having started games for both the Arizona Cardinals and Minnesota Vikings, gives the team hope. His career stats include a passer rating of 77.5 and a solid rushing ability, which could be crucial in the upcoming game.

The Miami Dolphins will be without wide receiver Jaylen Waddle for their upcoming game against the San Francisco 49ers due to a knee injury. Fellow receiver Dee Eskridge will also miss the game, while starting tackles Terron Armstead and Kendall Lamm return to the lineup after being inactive last week.

On the other hand, the 49ers will have key defensive players Nick Bosa and Dre Greenlaw active, despite some notable absences including tackle Trent Williams and running back Isaac Guerendo.