San Francisco stands at an inflection point in 2025, leaning on a rising core as the window on glorious runs tightens. Purdy carries the weight of a five-year, $265 million deal and must elevate a new supporting cast to keep the offense humming. Bosa remains elite, but a younger line around him requires more dominance to keep the defense rolling. Pearsall needs a breakout year as the No. 1 option, while Shanahan’s job security adds a pressure layer on every decision.

As the 49ers navigate this crossroads, fantasy managers should watch Purdy’s development, Pearsall’s opportunity window, and the defense’s ability to adapt with rookies ready to contribute. The blend of veteran expectations and a growing young backbone signals a potential regroup-and-rise season rather than a simple continuation of the ascent.

Jauan Jennings returns to 49ers practice after calf injury and a suspected contract holdout, setting the stage for an unsettled Week 1 at Seattle. His reintroduction comes with questions about speed, route timing, and overall conditioning after limited camp time. The SF offense may lean on Deebo Samuel, Brandon Aiyuk, and George Kittle early, while Jennings works to regain his role and trust in the offense.

Historical holdouts suggest a cautious ramp, and the calf risk adds another layer of risk for fantasy managers. If Jennings isn’t fully back by Week 1, Seattle’s defense could clamp down, making Jennings a risky Week 1 option with potential to trend up as he proves he’s fully operational in the following weeks.

Nick Bosa’s San Francisco deal sits at a high watermark with a five-year average around 34M, fueling the overpay debate as Bleacher Report highlighted him alongside Montez Sweat. The discussion hinges on the last two seasons: 19.5 sacks but fewer tackles, raising questions about value versus cost in fantasy terms. Parson’s market-shifting contract and comparisons to Watt, Garrett, Crosby, and Hunter frame the ROI discussion.

While the total value and age at signing matter, Bosa’s still-elite influence keeps him in the fantasy mix if SF’s defense remains top-tier and health cooperates. The narrative isn’t one-note: longevity and peak impact could swing value, especially as peers move into new market tiers. Fantasy managers should weigh health, team context, and the evolving edge-rush market before assigning blind risk to the tag.