Buffalo’s Monday night loss to Atlanta exposed a stalled offense and a defense that steadied only late. Across three drives after the 21-14 deficit, the Bills managed 39 yards on 14 plays, including a costly end-around miscue on third-and-1 that led to a punt. McDermott and Brady voiced frustration, signaling a need for simpler, more reliable play-calling. The bye week comes at the right time for Josh Allen and company to regroup before a Week 7 bye and a Week 8 date with Carolina.

Rams sit at 4-2 and head to London after a Maryland detour, with Puka Nacua and Blake Corum nursing ankle sprains and Tutu Atwell progressing toward a potential Sunday return. London-bound Jacksonville lurks, with Devin Lloyd and Quintin Morris out and Ventrell Miller stepping in as Coen and Gladstone’s Jaguars rebuild gains speed. Across the league, Brian Branch’s suspension looms for Detroit, Tua’s post-loss critique raises eyebrows, Titans hunt for stability after a coaching purge, Bijan Robinson fuels Atlanta, and the Rams’ leverage with a coveted 2026 first-round pick remains a talking point.

The Rams’ London clash looms as a major fantasy influence, shaping lineup decisions with injury updates and practice plans, while Jacksonville’s reshaped staff and depth charts add intrigue to a volatile divisional race. With the league buzzing from Lions discipline to Dolphin drama, the week promises big swings for fantasy rosters and betting angles alike.