Buffalo at Chicago in primetime Week 2 of the preseason hinges on depth-chart theater more than box-score glamour. Mitch Trubisky is slated as QB2 with the job to lose, and the night offers a clear chance to prove pocket poise and smart decision-making against his former club. Curtis Samuel and Elijah Moore stand out as potential breakout plays if healthy, with Moore especially positioned to seize a prominent role amid a thinner Bills WR corps. On defense, Buffalo looks to rookies Deone Walker and TJ Sanders to stack meaningful snaps, while Ed Oliver, DaQuan Jones and Larry Ogunjobi push the interior, and Tre’Von Edmunds squanders no opportunity against his old teammates. The safety group—Damar Hamlin, Taylor Rapp, and Cole Bishop—needs reps to validate Babich’s plans, with Samuel’s status adding another layer of intrigue.

Buffalo comes to Soldier Field for a Sunday night preseason date with Chicago in unsettled weather terms. Kickoff around 76 and humid, with storms possible and a dew point near 72 that could sap passing efficiency. The Bills entered with a reshuffled receiving corps and a QB competition behind Josh Allen, as Mitch Trubisky returns to the Chicago stage where he was once drafted. Fantasy angles tilt toward the Bills’ depth players and their backup QB reps: James Cook likely anchors the backfield, while Elijah Moore, Khalil Shakir, Tyrell Shavers and the veteran Curtis Samuel could carry the lightweight targets if top receivers sit out again. The Bears present a test of Bills depth and live-bullet play, with tempests potentially tempering big play options. Historical context notes Buffalo’s 35-13 win in 2022 behind a strong rush attack and a shallow passing line in that late-season clash. Odds react with Bills favored by 1.5 and a 39.5 over-under, but weather could nudge passing production down roughly 12% in rain, per some sportsbooks. The matchup on Aug. 17 remains a test of depth chart decisions that fantasy managers should monitor closely as rosters trim.

The Buffalo Bills, led by MVP quarterback Josh Allen, have sparked discussions around acquiring a star receiver after a stellar 2024 season, which saw them average nearly 31 points per game. Despite this, the Bills do not find themselves in dire need of a top-tier wideout. Yet, the ongoing contract saga of Terry McLaurin with the Washington Commanders raises questions about potential trade scenarios. Notably, a proposition involving Curtis Samuel and a first-round pick has surfaced.

While there's interest in bolstering the receiving corps, the Bills' current offensive success, without a true No. 1 receiver, indicates that the focus may instead shift toward capitalizing on existing talents, such as Stefon Diggs and Gabriel Davis. This strategic approach could bolster game performance without disrupting team chemistry.

After a challenging debut season with the Buffalo Bills, Curtis Samuel is poised for a significant comeback. The wide receiver, who struggled with injuries and recorded disappointing stats last year, is determined to bounce back. With only 31 catches for 253 yards and one touchdown, Samuel acknowledges the need for improvement but reports feeling confident and healthy as he prepares for the upcoming season.

Sidelined by a shoulder injury last year, Samuel knows that maintaining his health is crucial. His optimism, shared in an interview, hints at a renewed focus, promising fantasy managers that he is ready to contribute significantly to the Bills' offense in 2025.