Buffalo surged back from a four-minute deficit to beat Tennessee in a wild Week 1, with Derrick Henry’s big late run setting the stage before the Bills slammed the door in overtime. Josh Allen’s leadership and Ed Oliver’s strip-tackles anchored a grinding comeback, while Dion Dawkins kept the pocket intact and the run game honest. The win tightens the AFC narrative, signals heavier week-to-week tests ahead, and points to key fantasy angles around Allen, Diggs, and the Bills’ emerging depth in a brutal league schedule.

In fantasy terms, Allen’s rushing upside remains a cornerstone, Dawkins’ presence matters for protection and decoy runs, and Henry’s heavy workload in a loss casts a spotlight on Titans’ game plan and possible backfield pivots. The Jets loom next in a division grind that will test every Bills asset and every opponent’s game plan.