Prime-time Week 1 pits the Bills against the Ravens in Orchard Park with three Bills prop bets catching fantasy eyes. Dawson Knox to score anytime at +500, Keon Coleman at 40+ receiving yards, and James Cook at 60+ rushing yards headline the slate on DraftKings. Allen’s trust in Knox remains a factor, Coleman looks like a Year 2 breakout candidate, and Buffalo’s run game should stay balanced as they open NBC’s SNF slate.

The bets hinge on Knox’s red-zone chemistry with Allen, Coleman’s growing route discipline, and Cook’s capacity to grind out yards behind a cohesive line and a Bills offense that often leans on multi-pronged attack in primetime.