Buffalo Bills bettors have three clear angles this season: Joey Bosa, Keon Coleman, and Josh Allen each loom as solid overs plays in Caesars totals for 2025. Bosa, fresh to a new club, is pegged for 6.0 sacks, Coleman for 1,000+ receiving yards, and Allen for 26.5 TD passes, with injury status on Coleman watched closely. The bets ride on a high-powered Bills offense and healthy seasons from the trio, offering plausible paths to value in a loaded AFC landscape.

These Over bets hinge on durability and usage: Allen remains a TD-driving force, Coleman has upside in Joe Brady’s scheme, and Bosa’s pass rush could recapture a double-digit sack cadence in Buffalo. The board’s odds invite aggressive yet informed wagering, especially if Coleman’s groin issues clear and Bosa’s adaptation to a new environment pays off.