Five sophomore wide receivers stand out as potential fantasy league-breakers in 2025: Harrison Jr. in Arizona could command a larger target share with Murray and a better connection in Year 2; Rome Odunze climbs into Chicago as WR2 behind DJ Moore, smoothing a transition after a modest rookie year. Xavier Worthy in Kansas City faces a crowded room but has big-play ability and Mahomes’ trust to unlock weekly upside. Ricky Pearsall in San Francisco projects more opportunities with injuries and a clearer path, while Keon Coleman in Buffalo is set for a sneaky leap thanks to Josh Allen and a stable role after Diggs and Davis depart. The piece ties in draft rankings, ADP shifts, and red-zone dynamics to help fantasy managers chart a clearer second-year breakout course.

Across the board, the article emphasizes depth-chart context, quarterback health, and schedule softness as catalysts for upside. Sophomore leaps hinge on targeted volume, red-zone opportunities, and the ability to exploit game-script variety in offense schemes that prioritize pace and explosive plays. For managers, these five names offer a blend of floor and ceiling, with Harrison and Odunze offering the most secure path to meaningful fantasy returns in 2025. Pay attention to ADP movements and late-draft targeting windows to maximize value on these high-upside sophomores.