Week 1 kicks off with Buffalo hosting Baltimore in a high-stakes opener that doubles as a proving ground for the Bills’ revamped passing game and the Ravens’ mission to quiet playoff ghosts. Buffalo’s path to offensive balance hinges on a more complete receiving group and a safer, smarter attack around Josh Allen, who still stands as a top fantasy asset despite questions about WR1 depth.

Keon Coleman is the name to watch as Buffalo’s most intriguing Week 1 breakout candidate, with Cole Bishop and Dorian Strong under pressure to lock down roles after injury-plagued camps. Baltimore brings a tested, explosive offense led by Lamar Jackson, aiming to puncture a Bills defense that’s stayed stout in camp. Fantasy gunners should monitor target distribution, snap splits, and how Buffalo leverages Coleman to unlock Allen’s ceiling in the opener.

Bottom line for Week 1: Coleman could become a steady fantasy contributor if the Bills’ receiver corps stabilizes, Allen remains a top-tier passer, and Buffalo capitalizes on favorable matchups against Baltimore’s secondary. Baltimore’s own pass-catchers and Jackson’s ceiling remain live tournament options, but consistency will matter more than Week 1 fireworks.