Buffalo comes to Soldier Field for a Sunday night preseason date with Chicago in unsettled weather terms. Kickoff around 76 and humid, with storms possible and a dew point near 72 that could sap passing efficiency. The Bills entered with a reshuffled receiving corps and a QB competition behind Josh Allen, as Mitch Trubisky returns to the Chicago stage where he was once drafted. Fantasy angles tilt toward the Bills’ depth players and their backup QB reps: James Cook likely anchors the backfield, while Elijah Moore, Khalil Shakir, Tyrell Shavers and the veteran Curtis Samuel could carry the lightweight targets if top receivers sit out again. The Bears present a test of Bills depth and live-bullet play, with tempests potentially tempering big play options. Historical context notes Buffalo’s 35-13 win in 2022 behind a strong rush attack and a shallow passing line in that late-season clash. Odds react with Bills favored by 1.5 and a 39.5 over-under, but weather could nudge passing production down roughly 12% in rain, per some sportsbooks. The matchup on Aug. 17 remains a test of depth chart decisions that fantasy managers should monitor closely as rosters trim.