The Week 6 NFL slate closes with Patrick Mahomes and the Kansas City Chiefs hosting Jared Goff and the Detroit Lions in a high-profile, spread-tight showdown (Chiefs -2.5, 52.5 total). Monday brings a doubleheader: Bills at Falcons and Commanders at Bears, with sharp lines and bold promos driving action. The betting model leans Lions to stay within reach, Bills to cover more often, and Washington to handle Chicago, shaping DFS and prop bets across the board.