Khalil Shakir earns No. 8 on Bills 2025’s top-30 countdown after a breakthrough 2024 season that saw him post career highs in targets (100), receptions (76) and receiving yards (821) while Josh Allen leaned on him as Buffalo’s primary outside weapon. He locked in a four-year, $53 million extension, underscoring the team’s plans to lean on him again in 2025. With Josh Palmer and Elijah Moore adding, Shakir’s role remains pivotal though a persistent ankle sprain could delay Week 1 usage. The Bills’ offense should continue to funnel targets his way, especially if he maintains Week 1 readiness.

Buffalo’s 2025 outlook centers on Shakir as the WR1-ish talent in a revamped group that also includes Keon Coleman and Dalton Kincaid, plus a backfield led by James Cook. Shakir’s route-running elusiveness and catch-after-the-catch ability remain his calling cards, even as external additions pressure the defense to respect more options. The health question—an ankle sprain in August—remains the wild card that could shape his early-season workload and fantasy value.

Beyond Shakir, the countdown highlights Bills core contributors who shape fantasy upside: James Cook at running back, Connor McGovern at center, Tyler Bass as a reliable kicker, and a defensive line anchored by Ed Oliver, AJ Epenesa and DaQuan Jones, plus Tre’Davious White in the secondary. Together they form a high-upside, offense-driven core with room to grow as Buffalo chases a Lombardi.