The Arizona Cardinals have had a mixed bag of success with their second-round draft picks over the past decade. Players like Budda Baker and Trey McBride have emerged as stars, with Baker being a consistent Pro Bowler and McBride recording a record-setting season with 111 receptions. However, others like Andy Isabella and BJ Ojulari have underwhelmed, with Isabella never fully realizing his potential and Ojulari missing significant time with injuries.

In 2020 and 2016, the Cardinals traded away their second-round picks for high-profile players, DeAndre Hopkins and Chandler Jones, respectively. While these trades brought immediate impact, the opportunity to develop young talent was sacrificed. The latest picks, Max Melton and BJ Ojulari, remain to be seen in terms of their long-term contributions. As the Cardinals approach the 2025 draft, assessing the effectiveness of their second-round selections will be crucial for future roster development.