Thursday Night Football pits Seattle against Arizona in a compact NFC West clash with fantasy implications. Seattle carries a clean injury ledger, while Arizona navigates Will Johnson’s absence and a return for Paris Johnson up front. With James Conner sidelined, Trey Benson steps into a larger backfield role, and Marvin Harrison Jr. could see looks if passes find their mark. Sam Darnold’s erratic floor adds a wrinkle for anyone projecting the 49ers’ opponents. Expect a run-heavy, low-scoring grind in this divisional tilt.

For fantasy managers, Cardinals options may require speculative upside from Benson and Harrison Jr., while Seattle’s backfield and pass-game efficiency will hinge on game flow and possession. If Arizona can limit turnovers and lean on Benson’s burst, a contrarian DFS or streamer play could emerge. In short, this TNF should reward disciplined rostering and situational upside more than marquee names.

Arizona elevates Michael Carter and Anthony Goodlow from the practice squad to the active roster just hours before Thursday Night Football with Seattle, as James Conner is done for the season. Trey Benson steps in as Arizona’s RB1, and the team leans on a reshaped backfield in hopes of jump-starting a stagnant rushing attack. Six players are questionable, Paris Johnson Jr. is expected to play, and Seattle could get some reinforcements tonight as well.

Head coach Jonathan Gannon emphasized improving run efficiency and tailoring the game plan to Seattle, noting a different approach than what was used against San Francisco. The Cards must fix technique and execution to stay competitive, while the Seahawks anticipate a few returning players to aid their own effort on TNF.