Arizona's offense in the second preseason game vs Denver logged 49 snaps with 25 players involved. Jacoby Brissett led a five-play opening sequence and then steered the Cardinals to their lone score — an 11-play, 67-yard drive that culminated in Simi Fehoko's 16-yard TD pass. Brissett finished that possession 5-for-5 for 49 yards and did not play again, giving way to Clayton Tune for the majority of the game.

Clayton Tune (33/67) struggled to generate big plays, compiling 56 yards on 13 completions (2.8 yards per attempt). Most of his throws were short, with two 10-yard completions to Michael Carter and DeeJay Dallas and 11 total receptions for 36 yards on shorter routes. The Cardinals leaned on the backfield mix of Carter (23/47) and Emari Demercado (20/41), totaling 29 rushing yards on 15 attempts, with Demercado valued for his pass protection. Xavier Weaver, Simi Fehoko and Tejhaun Palmer led the receiving corps, with Fehoko adding the TD and Weaver making a key 17-yard first down while also drawing attention on a potential DPI. The offensive line featured notable names like Jeremiah Byers, Sincere Haynesworth and Nick Leverett handling the majority of snaps, though the top six linemen sat out or rotated. Injuries crept in early as Conner left the game with a knee issue after the third snap, prompting Haynesworth to step in. The result was a game that highlighted depth and development for Arizona, with inconsistent yardage but growing familiarity for Tune and the receiving group ahead of the regular season.