Arizona's 2025 X-Factor is Josh Sweat, a proven late-down edge whose fit with Jonathan Gannon could lift the Cardinals' revamped defense. Sweat's presence on third downs is expected to spark one-on-one matchups and raise the team’s pressure rate, while allowing teammates to flourish in complementary roles.

Alongside Sweat, Walter Nolen III, Will Johnson, and Darius Robinson provide a young, versatile front. Sweat’s floor-raising effect—more protection disruption than gaudy sack totals—should unlock the DL and help Arizona contend for a playoff push.