Patrick Mahomes opened KC’s preseason appearance with a 1-play, 1-yard TD drive after a Cardinals fumble, finishing 1-for-1 for 1 yard and a score. Gardner Minshew added a 2-yard rushing TD later, and Harrison Butker split the afternoon with a 58-yard FG. Arizona’s offense moved more consistently, with Kyler Murray completing 7 of 8 for 96 yards and an interception across two drives. Brissett threw for 81 yards and two scorers, including a 1-yard TD to Xavier Weaver as the Cardinals grabbed a halftime lead that turned into a 20-17 win. Arizona outgained KC 355-249, while front-line changes and depth-chart shuffles highlighted both teams’ preseason focus. Injuries to KC’s Jaylen Watson and other notable rotations added to the evaluative intrigue. Fantasy takeaway centers on Cardinals depth and potential late-round adds, with Chiefs’ focus on rest and depth pieces offering DFS angles in late-slate games.