The Arizona Cardinals are looking forward to a more prominent role in prime-time NFL matchups for the 2025 season after a lackluster schedule in 2024 that featured only one prime-time game. With the NFL full schedule release approaching, several potential matchups stand out that could draw significant national attention.

A game against division rival San Francisco 49ers is almost a given, as their history of rivalry captivates audiences. Similarly, a face-off against the Dallas Cowboys would be enticing, especially since Cardinals quarterback Kyler Murray has never lost at AT&T Stadium, adding an intriguing narrative. Another exciting matchup could be a showdown with the Cincinnati Bengals, highlighting the duel between former No. 1 picks, Kyler Murray and Joe Burrow. A game against the Green Bay Packers would also be compelling, pitting Murray against Jordan Love. The Cardinals are hopeful that these matchups will lead to a greater spotlight in 2025.