Arizona hosts Carolina in Week 2 with a chance to start 2-0 at State Farm Stadium, a feat not achieved since 2021. Gannon emphasized rapid three-phase improvement after Week 1 and adapting to Blount’s season-ending injury, pushing interchangeable players into elevated roles. Carolina counters with a mobile quarterback, a strong O-line, and Hubbard in support, plus emerging targets like McMillan. Week 2 will test Cardinals’ depth and how quickly the defense can gel behind its corners and pass rush.

Fantasy takeaway: Blount’s absence nudges opportunity across Arizona’s defense and depth chart, while Hubbard remains a focal point for Carolina. McMillan’s Week 1 flashes hint at red-zone and gadget usage, and the Cardinals’ secondary will be tested by Carolina’s balance. This game serves as a proving ground for Gannon’s plan and for players stepping into expanded roles across three phases.

Daniel Jones won Indianapolis’ starting job this preseason, posting a clear edge in accuracy and a higher PFF grade than Anthony Richardson, signaling a safer floor for Colts pass-catchers. The Jets plan a RB committee headlined by Breece Hall, with Braelon Allen, Isaiah Davis and possibly Donovan Edwards sharing reps, keeping fantasy upside diversified. Andrew Vorhees seized Baltimore’s left guard spot, while rookies Dylan Fairchild and Seattle’s interior linemen showed upside. Cardinals’ Max Melton and Will Johnson earned starting corner roles, and Tampa Bay’s Jacob Parrish emerged as a notable slot option. These battles set the tone for early-season fantasy boards and 2025 projections.