Colorado State University's football program has a storied history of NFL draft success, showcasing over 100 players since 1943. Recent notable picks include defensive end Mohamed Kamara, selected by the Miami Dolphins in the fifth round of the 2024 draft, and tight end Trey McBride, who was picked by the Arizona Cardinals in the second round in 2022. Other former CSU players who have made their mark in the NFL include Michael Gallup and Olabisi Johnson, indicating the program's ability to produce talent across various positions and rounds.

CSU's draft history highlights a range of success from first overall picks like Kelly Stouffer in 1987 to players chosen as late as the 451st pick. This depth illustrates the significant impact CSU has had on the NFL landscape, with its alumni continuing to perform at a high level in professional football.