Arizona trimmed to 53, signaling a fluid, week-to-week roster with heavy practice-squad planning. Surprise cuts included Simi Fehoko, DeeJay Dallas, and Darren Hall; Fehoko and Hall landed on Arizona's practice squad while Dallas moved on to the Panthers. Clayton Tune joined Green Bay after training camp with the Cardinals. Arizona filled its practice squad with versatile depth players such as Andre Baccellia, Elliott Brown, Jeremiah Byers, Michael Carter, Jake Curhan, Josiah Deguara, Kedon Slovis, Nick Leverett, Tejhaun Palmer, Elijah Simmons and Chigozie Anusiem, among others, while Walter Nolen, Bilal Nichols and BJ Ojulari sit on PUP and Justin Jones on IR.

Injuries and fluid mobility loom large for Week 1 depth, with Justin Jones on IR and Brewer back on the active roster after a cut. The roster moves underscore how ARI will rely on a strong practice-squad scaffold to absorb early-season gaps and potential injuries, while still keeping an eye on late cuts and waiver adds that can alter the Week 1 picture.