Jaylen Warren looks like a strong Week 2 start in PPR leagues, nursing a solid floor as a high-end RB2 while sharing work with Kenneth Gainwell. The Steelers’ matchup against Seattle offers a favorable environment, especially if Gainwell continues to struggle with efficiency. Warren’s quick, decisive runs and reception upside give him steady fantasy value, with the potential to push into the top tier of Week 2 backs if the Seattle defense stays vulnerable to both the run and short passes.

If Gainwell falters, Warren could absorb a larger workload and be Pittsburgh’s featured runner, a path that raises his ceiling beyond the typical RB2 range. The combination of Pittsburgh’s backfield dynamics and Seattle’s Week 1 struggles defending backs sets Warren up to deliver solid, usable Week 2 production in most formats.

Jakobi Meyers flashed as Geno Smith's top target in Week 1, drawing 10 targets and grabbing 8 for 97 yards in a Raiders win over New England. The early connection signals a sizable target share moving forward, with Meyers functioning as a trusted possession option and big-play threat. If Brock Bowers is limited by knee injury, Meyers could push into high end WR2 territory in PPR and toward WR2 in standard formats. If Bowers suits up, Meyers remains a solid WR3 with weekly upside, especially in a Week 2 Monday night test against the Chargers.

The Week 2 matchup and the ongoing discussion around Who Should I Start underline Meyers' volatility ceiling: volume-driven weeks when the offense commits to him, with a potential spike if the supporting cast is hindered. Managers should monitor Bowers status closely as this game approaches, as it will largely dictate Meyers' week plan and fantasy viability.

New Orleans faces a tough test as Spencer Rattler and a battered offense host San Francisco. With Taysom Hill, Foster Moreau, Trevor Penning, and potentially Taliese Fuaga sidelined, the Saints must push a more efficient passing game and smarter play design to avoid an 0-2 start.

For fantasy managers, focus on Rashid Shaheed, Chris Olave, and Alvin Kamara as the trio most likely to produce targets and yards if the Saints unlock play-action and get the ball into space. San Francisco’s defense remains elite up front and in coverage, so protection and precision from Kellen Moore and Rattler will be pivotal for any redemption day in week 2.