Week 3 brings major inactives for both New Orleans and Seattle. Saints sit seven players, including Chase Young, multiple blockers and receivers, reshaping the Saints’ frontline and depth. Seattle also rolls with a sizeable inactive list, led by Zach Charbonnet and several defensive backs and linemen, which tightens the Seahawks’ rotation and creates a clearer path for backups. Fantasy managers should expect amplified roles for reserves and adjusted game plans on both sides.

These absences tilt the DFS landscape toward opportunistic plays and riskier stacks. With key pieces out, targets and carries slide to players behind the listed starters, and defensive units may enjoy longer stints on the field. The matchup at Lumen Field becomes a test of depth, situational play-calling, and the ability of second-stringers to convert limited opportunities into fantasy dividends.

In short, depth charts get tested, and this game rewards those who can identify emergent contributors stepping into larger roles due to inactives. Lineup decisions should weigh the likelihood of elevated workloads for those players stepping in and the potential shift in offensive and defensive efficiency caused by these absences.

Seattle’s Week 1 inactive list reshapes the Seahawks’ game plan against San Francisco, with Bobo, Dareke Young and Uchenna Nwosu among seven SEA players out. The 49ers also rolled seven, trimming depth at multiple spots. Expect increased opportunities for Seattle’s top receivers and for linebackers stepping into larger roles, as both teams adjust to missing contributors in a considered Week 1 matchup.

Key Seahawks absences include Bobo and Young at wide receiver and Nwosu on the edge, while the 49ers sit several depth players to open the door for others. In fantasy terms, the biggest shifts come from who absorbs the extra targets and snaps on SEA’s offense and who gains reps in SF’s depth chart, potentially altering streamer and DFS value in a marquee Week 1 battle.

Risner’s visit to Seattle ends with a Bengals deal, leaving the Seahawks scrambling for interior line depth. Risner can play guard on either side, but Cincinnati snagged him to bolster protection and the run game. Seattle’s depth behind the starters is thin: Zabel at left guard is locked, Bradford figures to start at right guard, and the rest includes Oluwatimi, Josh Jones, Laumea, Laumea’s practice-squad return, and a pair of rookies in Cabeldue and Richman. Seattle may ride with the current group and hope youngsters develop together.

Seattle moved quickly after the waiver deadline to assemble its initial practice squad, keeping core depth intact while juggling two seventh-rounders and late-round linemen. Damien Martinez and Ricky White III were waived from the 53-man roster but are on Seattle’s practice squad, signaling a focused RB and WR pipeline. Mason Richman and Bryce Cabeldue remain on the roster as experimental linemen. Rylie Mills starts the season on the non-football injury list, and Jerrick Reed II plus Sataoa Laumea have mixed fates. The club also re-signed Quinton Bohanna and Federico Maranges (IPP), with Jamie Sheriff and Jacardia Wright among the other reported returnees. The Seahawks continue to leverage the IPP slot and cap restrictions while keeping options open for Week 1 and beyond.

In parallel, the Seahawks’ re-signings and practice-squad structure highlight Seattle’s emphasis on internal development and immediate depth at running back, receiver, and the interior line. The International Pathway Program designation adds a 17th slot, offering strategic flexibility as Seattle navigates two- or three-year veteran restrictions. With 16 practice-squad slots (plus IPP), Seattle is staking a clear plan for practice competitiveness, injury coverage, and future promotions as the season unfolds.