The 2025 fantasy football best ball running back rankings have been updated as draft season heats up. Saquon Barkley leads the pack after a stellar season, amassing over 2,000 rushing yards and solidifying his top-tier status. Bijan Robinson and Jahmyr Gibbs follow closely, both showcasing their skills as key offensive players. The rankings stress the importance of selecting running backs early due to their impact on scoring outcomes in best ball formats, where lineups are set automatically. With the NFL season on the horizon, analysts emphasize the need to prepare strategically, utilizing tools like draft assistants and simulators to gain an edge over competitors.