Mac Jones says he’ll start against the Rams, challenging Purdy’s command of SF’s offense. Purdy stressed readiness and leadership after toe protection in the last game, while Shanahan’s run-first approach tests a line missing Kittle and Aiyuk. Colby answered with all 66 snaps, elevating his run blocking as SF eyes Week 5 and potential midseason reinforcements for the pass rush.

Mac Jones is set to start for San Francisco after a knee scare, with Adrian Martinez not elevated. Eli Apple was added from the practice squad for Sundays game against Jacksonville, signaling confidence in the rest of the depth chart. Ricky Pearsall and Jauan Jennings are questionable but likely to play, keeping Bourne, Robinson, Valdes-Scantling and Skyy Moore as viable targets if one sits. Colby is questionable; Moss or Zakelj could step in. Brandon Aiyuk’s absence remains the defining storyline for the offense.

If Pearsall and Jennings sit, the 49ers would lean on a shallow WR corps; if one plays, expect a broader distribution with the expected nod to Bourne and the Chiefs pairing of Robinson, Valdes-Scantling and Moore. The 49ers will list inactives 90 minutes before kickoff at Levi’s Stadium.

Week 4 looks stabilized at quarterback for the 49ers as Brock Purdy nears a return from a toe injury, reducing major fantasy risk at the position. Mac Jones remains a questionable backup, but Purdy’s health is the backbone for San Francisco’s Week 4 upside.

In the receiving corps, Jennings and Pearsall carry injury risk. If both sit, Demarcus Robinson and Kendrick Bourne would step into lead roles, giving fantasy managers a late-week option with Robinson’s season debut on deck. Other listed veterans and depth pieces (Watkins, Green, West, Colby, Davis) create depth concerns more than fantasy pivots unless top WRs are sidelined.

Week 4 looming against Jacksonville keeps an eye on injuries as the key differentiator for lineups. Stay tuned to the final injury report and readiness news to gauge start/sit decisions for the 49ers’ pass game and potential DFS value.